Correlation between Alopecia areata & smoking?

This post is adapted from Alopecia World forum

and this is what I replied to the discussion:

"There is no scientific paper suggest that there is a significant correlation between smoking & alopecia areata yet, I am not aware of any test/ survey being done on the matter also.

1. It is widely accepted both by alopecia patients and scientists/ dermatologists that alopecia areata can be triggered by stress. Stress also comes in various form, physical/ physiological, psychological, pathological or any combinations of the mentioned..etc. Eventhough there is no scientific evidence on the connection between smoking & alopecia, I believe that smoking can be a predisposing factor to alopecia areata. (As per any foreign event/ particles in the body could induce an auto-immunity state). In short, smoking is a form of physical stress of the body indirectly and to the lungs directly.

2. Smoking as a mean to relax the mind and mental/emotional state, statement is valid & factual. One thing for sure, it is not relaxing to the lung and also the heart. While you're relaxing your mind and resting your brain at one time, at the same time you're also comprising the well being of the other vital organs of the body. Why don't you find other means to relax your mind without comprising the health of the other parts of your body. Just as much as you love your mental status/mind/brain, you must love your lungs and heart as well (in addition to the liver and kidney which made up the 5 vital organs of the body).

3. a little more fact about the lung, the lung surface are generally and mostly covered with thin pneumocytes type I (Lung cell type 1) which is responsible for gas exchange (Oxygen-Carbon dioxide exchange), oxygenated blood subsequently distributed by the heart to the entire body. Pneumocytes type II, on the other hand produce surfactant that provide integrity to the lung (thus preventing it from collapsing-atelectasis). Pneumocytes type I eventhough are plenty, their biological component is that it is higly susceptible to toxic insults/ infiltration and they do not regenerate/ or replicate, meaning these cells responsible for gas exchange does not regenerate after the cells die. The lack of cells for gas exchange, will result in lacking of oxygenation, and the tissues send signals to the body to increase breathing rate and heart rate, in order to restore the constant and adequate oxygenation to all body tissues. Well, it is true, some have smoke heavily for decades and yet still healthy, we must praise God that He had created reserve "lung tissues"- functional reserve to sustain our living, our lung's functional reserve is at least 50%-75%, meaning we can still live healthily with one side of the lung removed. So what, some may say, like my own grandfather, who smoked for over 70 years and he is now 97 years old.

I believe, those who smoke and still live long, could live even much longer if they didnt smoke.In conclusion (everyone at this time will say, Praise the Lord...lol). It doesnt matter much if smoking worsens alopecia areata or not, because it matters more that smoking actually add burden to the lung directly and the heart indirectly. Well, the lung and the heart are definitely more important than my hair.

Hair is just another ascessory tissues (play some role) to the skin, while the lung and the heart are major vital organs that sustain the quality of life and eventually life itself! Only if the heart and the lungs are visible on the outside of our body, the society then will pay a lot more attention to them!I dont mean to give you a lecture, I presume your occasional cigar would be more like a weekly habit rather than a daily habit.

I agree that smoking does add to the fact that can provide some form of calmness to the mind and relieve anxiety and ease emotional stress. My motto "I love my lung and my heart just as much as I love being calm to my mind", so I'll find another way to relax. If you're not thinking of quitting smoking, my next advice would be "Moderation is the key".

Take care and God bless."

Joshua

Air France Flight 447 Tragedy - a mouthpiece for opportunist?

Air France Flight 447 scheduled on 1st June 2009 crashed into the Atlantic Ocean hours after taking off from Rio De Janeiro enroute for Paris.

A tragic accident that took many beautiful lives and changed thousands of lives forever. While the family and friends of the victims still mourning over the loss of their loved ones. A wound that would take years or even decades to heal yet will still live a scar in one's broken heart, people around the globe watched the news with sympathy to begin with. Soon enough, their sympathy fades as soon as the media coverage fades away.

This tragic accident (less than a month old) which took so many wonderful lives has already been used as a shameful mouthpiece/ argument material for some ignorant quarters of the society. While there are many examples, I would only pick two most ridiculous, ignorant of how this tragedy has been used to sastify one's hunger to be right or correct (= one that thinks they know the best)

1. I have come across a comment from a religious person of the Christian faith, who with pre-conceived judgement said that probably none of the 228 person on Flight 447 from Rio to Paris on June 1st 2009 have prayed sincerely to God for a safe journey.

This is an outrage statement! This comment was made without a sense of human sympathy/ sensitivity for the victims and their friends and family! In addition, it is an insult to the Christian faith and God. God and the Bible has in NO where warrants or validate that people with the Christian faith would not endure hardship, sickness, pain and eventually death itself in life! I am deeply disgusted with such statement.

2. An atheist quoted the tragic event as an incident to prove the inexistence of God.

Rubbish! It's like seeing a bird on the ground for that moment and proclaimed that the bird cannot the fly the next minute. Without sense of sadness and sympathy for the victims especially for those with faith in God, the person who made the statement rob the already broken hearts of many to be used for his personal belief/ argument. (I'm not going into the debate of the Existence of God)

The two outrages statments made above must be condemned by all right-thinking people. Let us continue to set our prayers, thoughts and comforts to the family and friends of the victims of flight 447. On a personal note, both who made the statements are actually playing god themselves. The former acted if he is Deputy God, speaking on behalf of God while the later acted if he is Guardian of God by declaring God does not exist.

let us all set our heart and thoughts in a good spirit with love and kindess towards all.

My thoughts and prayers go out to all affected by this tragic accident.

Joshua

Global economy slump, who are the victims?

With everyday headline coverage of the global economy crisis in the media. Who is the most unfortunate in victims of all?

Definitely not the shareholders or executive officers or board of directors of Chrysler or General Motors of the US Giant auto vehicle industries. The most affected would be the middle classes and more so for the general workers working in various plants which faces the threat of unemployment and ultimately the lost of the mean to provide to the family.

While the economists, bosses, executive officers, shareholders worry about their stock exchange, and restructuring of their bussiness and companies, they have forgotten the most fundamental business or corporate ethics of looking after the welfare of the employees, who some have worked many years and loyally. For most, people working in blue collar jobs are not only often underappreciated but they are first ones to be kicked out in the face of crisis in the corporate/ business world.

Some bosses touched by the torn of human conscience have even agree to reject a pay rise in their salary. What about the hundreds of thousands or even millions dollars of expenses paid by the company/ business for family vacations, food, leisures, or some even private jets?

It is most shocking to see some top executive officers besides being paid more than millions a year, are claiming other mostly non-essential benefits from the company often more than their basic salaries!

I am not saying whether the executive officers should be paid or given those expenses or not but how about those working as blue collar jobs?

Far more unfortunate are those who are already living under poor conditions of less than a dollar a day and without the excess of clean water and basic sanitation!

They continue to go hungry, thirsty, sick, cold as usual or perhaps more during the global economy crisis when charitable organisations are among the hardest hit in the current economy downturns.

While many groups fight for social equality in various causes around the globe, one of the most injustice situation remains by large in silence. The poorest among the poor especially in Africa, parts of Asia and Latin America has to plead for help instead of fighting for fair and equal treatment they should be receiving.

In short, with the current global economy slump, who are the victims?

The answer would be those who are already victims of social and economy injustice before beginning of the the current economy crisis.

Joshua

People sent from heaven

On 15th May 2009, it was exactly the day two years ago when I reached the United States the for first time by boarding a plane with a flight ticket bought by a person (including her wonderful friends & family) that at the end proclaimed that it was a gift from God to her.

Eversince, this question of thought was raised in me "What did I do to deserve such kind and generous treatment?", its been years when I started pondering deeply on the question. I thought from the east to the west in search for the answer, thinking the best things or best attributes I have or done in the past (eventhough it is improper to think highly on one ownself) to deserve such kindness and generosity, but all is in vain...

At last, after nearly two years of search for the answer, the actual answer does not come and cannot be found from me. An answer from heaven has humbled me that it was not really about me, myself or I but the true answer lies within the giver herself.

Just as much as a bird is to fly or a dog is to beg for food :) (Let me try again...)

Just as much as God is to love, the giver herself (which I am the taker/recipient) is generous and kind. Yes, the answer to my question is NOT what I have done or not done or even who I am BUT it is who the giver/ person is WHICH is nothing lesser than a kind and generous soul sent from heaven.

It is not who I am or or what I have done BUT it is about who the giver is WHICH is a kind and generous soul.

I am blessed with so many genuine and kind friends. I thank the LORD everynight for all of you.

Thank you for being yourself/ yourselves, nothing lesser than a kind and generous soul.

Thank you.

Joshua

Response to intensive 3 months of prednisone treatment for AA

My response to three months of prednisone treatment for Alopecia areata. (As posted on Alopecia World website)



I am going to voice my opinion as brief as possible into three aspect Physiologically, Philosophically & Psychologically. I'm into veterinary medicine and we even use prednisone for animals but never longer than 7 days. However, I need more specification/ details in term of the dosage of prednisone and the route of administration. However, my response is based on the recommended prednisone dosage being used over this three months of treatment (given systemically).

The physiological aspect:

Side effects of Prednisone:
Major
1. Risk of developing diabetes
2. Weight gain (also increased risk of Cushing's syndrome- hyperadrenocortism)
3. Facial swelling / ascites/ edematous
4. Depression, euphoria, or behavioral changes
5. Fatigue or lethargic
6. Vision impairment
7. Ulcers / Mouth sores
8. Osteoporosis
9. Insomnia
10. Joints & abdominal pain
11. Cataracts
12. Anxiety
13. Blood vessels diseases

Minor
1. Rash
2. Diarrhea
3. Frequent urination

In short, I am strongly against the use of Prednisone for more than 7 days as recommended for the treatment of Alopecia areata and what more for 3 months. ( Again, very dosage dependent)

The philosophical aspect:
One must set priority right, naturally and normally in our body as designed by God. Hair is just a part of the body, when we are compromising the conditions of other major organs and vital organs and the IMMUNE SYSTEM in the sake of getting our hair back, I seriously urge people to re-examine their thoughts and decision. The compromises made would probably led to one the side effects mentioned above (Under recommendation, the use of prednisone is not more than 7 days or give and take 14 days). Three months is almost 12 folds higher. One must be compromising their quality of life and even their LIFE if agree to be subjected to the treatment regime. In short, it is philosophically unwise when one opt to regain a non-vital part of the body by compromising other vital organs and even LIFE itself!

The psychological aspect:It would be thrilling and exciting to have my hair back. It would be perfect and awesomely great if I can have my hair back just with a simple faith without compromising my quality of life and my loved ones around me. I have been living with AA for more than 20 years and with AU for more than 6 years. I would definitely sacrifice alot for my hair to grow back as long as my sacrifices are practical, logical and sensible (i.e the more people I help, the more hair I get...etc) In short, our psychology needs to grow through proper thoughts and knowledge together with practicality and wisdom.

AT THE END I STRONGLY OPPOSE TO THE ABOVE TREATMENT REGIME & WOULD NEVER RECOMMEND IT TO ANYONE EVEN IF THE TREATMENT CAN WORK 100% EFFECTIVELY.

I couldn't read all the response to this discussion but I have read that some are willing to take this kind of treatment regime and some are trying for more than a few weeks already. I would like to add that some are taking calcium supplements to prevent the side effects of having osteoporosis while treating alopecia with long-duration of prednisone. Let me remind everyone to remember the amount of burden one is putting on the kidney. Kidney has to work extra hard for drug elimination and calcium mineral. The liver has to work extra hard for drug metabolism. The heart has to work extra hard due to the increase of blood viscosity due to the effect of drug, calcium supplements together with the ongoing comprimising of liver and kidney.

AGAIN, I AM STRONGLY AGAINST THE USE OF PREDNISONE FOR MORE THAN ONE MONTH (INJECTABLE into the body system) /TWO MONTHS (ORALLY) FOR THE TREATMENT OF ALOPECIA AREATA. * Local subcutaneous injection on the scalp are still acceptable once every two months (three times = six months)

SOME MAY DISAGREE WITH ME BUT THIS IS TOTALLY MY OWN OPINION. NO INTENTION TO OFFEND ANYONE. THANK YOU.

Joshua

Easter Day reflection

Hi,

I know it's more than a week since Easter but nevertheless the Lord is still risen, aren't he? Here's some youtube reflection that I would like to share.

Hope everyone had a blessed Easter. Praise the Lord.

Joshua

At the cross...

Holy Thursday reflection

As the christian calendar marks today as the Holy Thursday with several significant occasions, it was the official starting of the passion of Christ when he was betrayed into the hands of those who wanted him to be killed.

Christ knew what was going to happen to him and felt the intense burden and heartache that he had on his shoulder when he prayed to Heavenly Father in Gethsemane. If we were to go back to that particularly time, knowing that he is Christ...what would be our reaction? Run away or fight for him? It was not for us to decide.

Let us all, christians (and non-christians) reflect on the beginning of this historical event that transcended across our physical realm of time and matter.

Let us reflect on the creator of heaven and earth that call us his friends on this special night:

WHAT A FRIEND WE HAVE IN JESUS



Now, let us focus our spirit and mind on Christ who loved us so much...

TURN YOUR EYES UPON JESUS

*This series of blog is specially dedicated to people of all faiths (including atheist, agnostics), as all us learn about each others' different faith and so at the end of the day, we respect other people's choice without being judgemental and narrow-minded.

*However, this blog is not for discussion or debate forum for inter-faith matters.

* I just wanted people to know what Christianity is all about, just as how much I am learning about others' faith and thus respecting their belief.

* Hope all is greatly inspired and to christians, hope you find strength in your faith again.

Joshua